SCHEMBL4049073

SCHEMBL4049073

Cc1c[c]c(-c2c(C(N)=O)[nH]c3ccc(Cl)c(F)c23)c(/C=C/C#N)c1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAP2 P11137 9/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2004536 0.76 MAP2 (0.40) MAP2
SCHEMBL2004540 0.76 MAP2 (0.40) MAP2
SCHEMBL12228602 0.73 MAP2 (0.40) MAP2
SCHEMBL2004538 0.72 MAP2 (0.40) MAP2
SCHEMBL14116072 0.71 MAP2 (0.40) MAP2
SCHEMBL12250379 0.71 MAP2 (0.39) MAP2
SCHEMBL14115910 0.70 MAP2 (0.46) MAP2
SCHEMBL1997740 0.70 MAP2 (0.38) MAP2
SCHEMBL12228552 0.70 MAP2 (0.38) MAP2
SCHEMBL1997869 0.70 MAP2 (0.38) MAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2078029-A2 ENANTIOMERICALLY PURE PHOSPHOINDOLES AS HIV INHIBITORS IDENIX Pharmaceuticals, Inc. (US) 2009-07-15 EP disclosed
WO-2008042240-A9 ENANTIOMERICALLY PURE PHOSPHOINDOLES AS HIV INHIBITORS IDENIX PHARMACEUTICALS INC (US) 2008-08-07 WO disclosed
WO-2008042240-A2 ENANTIOMERICALLY PURE PHOSPHOINDOLES AS HIV INHIBITORS IDENIX PHARMACEUTICALS, INC. (US) 2008-04-10 WO disclosed