SCHEMBL404924

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL439184	0.93	KDM4E (0.68)	KDM4ERECQLPDE5APARP1PARP2
	SCHEMBL403178	0.89	PDE5A (0.78)	KDM4ERECQLPDE5APARP1PARP2
	SCHEMBL400477	0.89	KDM4E (0.58)	KDM4ERECQLPDE5APARP1PARP2
	SCHEMBL400090	0.86	PDE5A (0.78)	KDM4ERECQLPDE5APARP1PARP2
	SCHEMBL404509	0.86	PDE5A (0.57)	KDM4ERECQLPDE5APARP1HCAR2
	SCHEMBL403265	0.85	KDM4E (0.59)	KDM4ERECQLPDE5APARP1PARP2
	SCHEMBL27771771	0.85	KDM4E (0.61)	KDM4ERECQLPDE5APARP1PARP2
	SCHEMBL401612	0.83	KDM4E (0.59)	KDM4ERECQLPDE5APARP1PARP2
	SCHEMBL30176876	0.83	PARP1 (0.73)	PARP1PARP2TUBB4ATUBBTUBA3C
	SCHEMBL405899	0.82	KDM4E (0.56)	KDM4ERECQLPDE5APARP1PARP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.