SCHEMBL40495

SCHEMBL40495

[CH2]O[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL10880749 0.67
SCHEMBL319527 0.61
SCHEMBL8404066 0.61
SCHEMBL9219479 0.61
SCHEMBL10799457 0.61
SCHEMBL16175 0.61
SCHEMBL9705842 0.61
SCHEMBL9622076 0.55
SCHEMBL18529807 0.55
SCHEMBL6026507 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5157 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2991655-B1 COMPOSITIONS AND METHODS FOR ALTERING SECOND MESSENGER SIGNALING MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2024-04-10 EP claimed
CN-117403220-A Sheet aluminum passivating agent for cold-coating zinc coating, preparation method and application 湖南金磐新材料科技有限公司 2024-01-16 CN claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
US-20230321228-A1 VACCINE ADJUVANTS AND METHODS OF SYNTHESIZING AND USING THE SAME EUAGORE, LLC 2023-10-12 US claimed
EP-4178937-A1 VACCINE ADJUVANTS AND METHODS OF SYNTHESIZING AND USING THE SAME Amyris, Inc. (US) 2023-05-17 EP claimed
CN-115836042-A Vaccine adjuvants and methods of synthesis and use thereof 阿米瑞斯公司 2023-03-21 CN claimed
CN-115785337-A Low-dielectric and high-thermal-conductivity silicone adhesive compound and preparation method and application thereof 广东工业大学 2023-03-14 CN claimed
EP-3649135-B1 SYNTHESIS OF HALICHONDRINS HARVARD COLLEGE (US) 2022-12-28 EP claimed
US-11352324-B2 Methods MEDIMMUNE LIMITED (GB) 2022-06-07 US claimed
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
US-20010029028-A1 Method and apparatus for combinatorial chemistry FOOTE, ROBERT S. 2001-10-11 US claimed
WO-2000066259-A1 METHOD AND APPARATUS FOR COMBINATORIAL CHEMISTRY UT-BATTELLE, LLC (US) 2000-11-09 WO claimed
EP-1005478-A1 RIBONUCLEOSIDE-DERIVATIVE AND METHOD FOR PREPARING THE SAME Pitsch, Stefan (CH) 2000-06-07 EP claimed
EP-0558215-B1 Novel methods and compounds for the preparation of carbacephems LILLY CO ELI (US) 1999-09-15 EP claimed
WO-1999009044-A1 RIBONUCLEOSIDE-DERIVATIVE AND METHOD FOR PREPARING THE SAME PITSCH STEFAN (CH) 1999-02-25 WO claimed
EP-0596015-A1 SUBSTITUTED BETA-LACTAM COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS AND PROCESSES FOR THE PREPARATION THEREOF. SCHERING CORP (US) 1994-05-11 EP claimed
US-5278332-A Derivatives of cyclohexane PERSTORP AB (SE) 1994-01-11 US claimed
WO-1993002048-A1 SUBSTITUTED BETA-LACTAM COMPOUNDS USEFUL AS HYPOCHOLESTEROLEMIC AGENTS AND PROCESSES FOR THE PREPARATION THEREOF SCHERING CORPORATION (US) 1993-02-04 WO claimed
EP-0021841-B1 2,3-DIALKOXY-1,4-QUINONE DERIVATIVES; METHOD OF PRODUCING 1,4-QUINONE DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 1984-10-24 EP claimed
EP-0021841-A2 2,3-Dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives Takeda Chemical Industries, Ltd. (JP) 1981-01-07 EP claimed