Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045018 | 0.90 | DPP4 (0.48) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4053303 | 0.89 | DPP7 (0.47) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4043977 | 0.88 | DPP4 (0.44) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4051774 | 0.88 | DPP4 (0.44) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4049054 | 0.86 | DPP4 (0.52) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4052757 | 0.82 | DPP4 (0.48) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4044435 | 0.81 | DPP4 (0.47) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4043693 | 0.81 | DPP4 (0.47) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4045289 | 0.81 | DPP4 (0.47) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4050902 | 0.80 | DPP4 (0.46) | DPP4DPP7DPP8DPP9CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |