Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055033 | 0.94 | ALOX5AP (0.35) | CYSLTR2CYSLTR1ALOX5APFFAR1AKR1B1 | |
| SCHEMBL4052947 | 0.92 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4052958 | 0.85 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1ALOX5APFFAR1AKR1B1 | |
| SCHEMBL4053959 | 0.85 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL13765255 | 0.85 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4058205 | 0.83 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1ALOX5APFFAR1 | |
| SCHEMBL13771077 | 0.83 | CYSLTR2 (0.35) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL13765256 | 0.83 | CYSLTR2 (0.35) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL13765258 | 0.83 | CYSLTR2 (0.35) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4058907 | 0.83 | CYSLTR2 (0.35) | CYSLTR2CYSLTR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | claimed |
| EP-1560834-B1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL LAB (ES) | 2008-06-25 | — | — | EP | claimed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| EP-1560834-B1 | NEW TRICYCLIC DERIVATIVES AS LTD4 ANTAGONISTS | ALMIRALL LAB (ES) | 2008-06-25 | — | — | EP | disclosed |