Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 3/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055410 | 0.89 | CNR1 (0.50) | CNR1CNR2ELANESCN9APOLB | |
| SCHEMBL13691011 | 0.89 | CNR1 (0.49) | CNR1CNR2ELANEPOLBPTGER4 | |
| SCHEMBL4055245 | 0.89 | CNR1 (0.49) | CNR1CNR2ELANEPOLBPTGER4 | |
| SCHEMBL1219308 | 0.88 | CNR1 (0.49) | CNR1CNR2ELANESCN9APOLB | |
| SCHEMBL13690980 | 0.87 | CNR1 (0.47) | CNR1CNR2SCN9APOLBPTGER4 | |
| SCHEMBL4059046 | 0.87 | PTGER4 (0.48) | CNR1CNR2POLBPTGER4HTR3A | |
| SCHEMBL13691041 | 0.85 | PTGER4 (0.50) | CNR1CNR2SCN9APOLBPTGER4 | |
| SCHEMBL4058848 | 0.85 | PTGER4 (0.50) | CNR1CNR2SCN9APOLBPTGER4 | |
| SCHEMBL1214282 | 0.83 | CNR1 (0.49) | CNR1CNR2ELANESCN9APOLB | |
| SCHEMBL1218709 | 0.82 | CNR1 (0.44) | CNR1CNR2ELANESCN9APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |