Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052489 | 0.92 | MCHR1 (0.79) | MCHR1CYP3A4KCNH2 | |
| SCHEMBL1365095 | 0.89 | MCHR1 (0.78) | MCHR1 | |
| SCHEMBL15249802 | 0.89 | MCHR1 (1.00) | MCHR1CYP3A4KCNH2 | |
| SCHEMBL15238604 | 0.88 | MCHR1 (0.85) | MCHR1CYP3A4KCNH2 | |
| SCHEMBL4048098 | 0.84 | MCHR1 (0.79) | MCHR1 | |
| SCHEMBL1365170 | 0.83 | MCHR1 (0.76) | MCHR1 | |
| SCHEMBL15238614 | 0.82 | MCHR1 (0.82) | MCHR1CYP3A4KCNH2 | |
| SCHEMBL13748710 | 0.80 | MCHR1 (0.63) | MCHR1CYP3A4KCNH2 | |
| SCHEMBL1366642 | 0.80 | MCHR1 (0.66) | MCHR1CYP3A4KCNH2 | |
| SCHEMBL1367992 | 0.80 | MCHR1 (0.79) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |