SCHEMBL4050183

SCHEMBL4050183

C=CCC(F)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28769395 0.97
SCHEMBL278696 0.80 MAPT (0.37)
SCHEMBL28084718 0.76
Bicarbonate SCHEMBL2034325 0.76 GRIK1 (0.40)
SCHEMBL10694895 0.75
SCHEMBL11188609 0.75 GRIK1 (0.41)
SCHEMBL31636 0.75 GRIK1 (0.48)
SCHEMBL10457331 0.73 CYP2C19 (0.35)
SCHEMBL31299617 0.72 GRIK1 (0.46)
SCHEMBL891727 0.72 GRIK1 (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0230144-B1 FLOW REACTOR SYSTEM MERRELL DOW PHARMACEUTICALS INC. (US) 1989-03-29 EP claimed
EP-1521738-B1 METHOD FOR MAKING NITRILE COMPOUNDS FROM ETHYLENICALLY UNSATURATED COMPOUNDS INVISTA TEXTILES (U K ) LTD (GB) 2017-11-01 EP disclosed
EP-1521736-B1 MAKING NITRILE COMPOUNDS FROM ETHYLENICALLY UNSATURATED COMPOUNDS INVISTA TECHNOLOGIES SARL (CH) 2017-09-13 EP disclosed
CN-102803239-B Compounds having bladder detrusor muscle contraction activity and urethral sphincter relaxation activity ONO PHARMACEUTICAL CO 2015-04-15 CN disclosed
CN-102378624-B thickening polymer in powder form SEPPIC SA 2014-01-22 CN disclosed
CN-102803239-A Compounds having bladder detrusor muscle contraction activity and urethral sphincter relaxation activity ONO PHARMACEUTICAL CO 2012-11-28 CN disclosed
CN-102378624-A Novel thickening polymer in powder form SEPPIC SA 2012-03-14 CN disclosed
US-7531682-B2 Method for making nitrile compounds from ethylenically unsaturated compounds RHODIA POLYAMIDE INTERMEDIATES (FR) 2009-05-12 US disclosed
US-7442825-B2 Making nitrile compounds from ethylenically unsaturated compounds RHODIA POLYAMIDE INTERMEDIATES (FR) 2008-10-28 US disclosed
CN-100404751-C Method for dyeing or printing cellulose-containing fibre materials using disperse dyes CIBA SC HOLDING AG (CH) 2008-07-23 CN disclosed
WO-2000017250-A1 DISPERSANT BASF AKTIENGESELLSCHAFT (DE) 2000-03-30 WO disclosed
WO-2000008068-A1 COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2000-02-17 WO disclosed
EP-0970529-A1 METHOD FOR PRODUCING SHAPED BODIES FOR LITHIUM ION BATTERIES BASF AKTIENGESELLSCHAFT (DE) 2000-01-12 EP disclosed
CN-1044711-C Hardenable pulverous fluor-containing polymer, preparation of same and application of same in pulverous coatings EIF ATOCHEM S A (FR) 1999-08-18 CN disclosed
CN-1214691-A Process for preparation of N-methyl-D-phenylalanyl-N-[1-[3-[(aminoiminomethyl)-amino] propyl]-3,3-difluoro-2-oxohexyl]-L-prolinamide HOECHST MARION ROUSSEL INC (US) 1999-04-21 CN disclosed
CN-1199794-A Method of treating dyed, natural of synthetic polyamide fibre materials CIBA GEIGY AG (CH) 1998-11-25 CN disclosed
WO-1998044576-A1 METHOD FOR PRODUCING SHAPED BODIES FOR LITHIUM ION BATTERIES BASF AKTIENGESELLSCHAFT (DE) 1998-10-08 WO disclosed
CN-1087359-A Powdered hardenable fluorinated copolymer, its preparation method and the application in powder coating thereof ATOCHEM ELF SA (FR) 1994-06-01 CN disclosed
CN-86104207-A The pesticidal use of many halogen alkene derivatives 1987-04-01 CN disclosed
CN-86101268-A The preparation method of new peptidase inhibitors 1987-02-04 CN disclosed