Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.76 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.76 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.76 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.76 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.73 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.65 |
| ▸ | CDK8 | P49336 | 2/20 | 0.61 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.59 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.59 |
| ▸ | MARK3 | P27448 | 1/20 | 0.59 |
| ▸ | FRK | P42685 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.59 |
| ▸ | STK3 | Q13188 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049642 | 0.91 | MAPK14 (0.79) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL16317155 | 0.89 | MAPK14 (0.75) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL4057287 | 0.88 | MAPK14 (0.73) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL14095664 | 0.86 | MAPK14 (0.87) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL4056230 | 0.86 | MAPK14 (0.86) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2081965 | 0.85 | MAPK14 (0.83) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL13296981 | 0.85 | MAPK14 (0.73) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL3192778 | 0.85 | MAPK14 (0.85) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL4052247 | 0.85 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL12245431 | 0.85 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312349-A1 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC | 2009-12-17 | — | — | US | disclosed |
| US-20090312349-A1 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC | 2009-12-17 | — | — | US | disclosed |
| EP-1836173-A4 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS LLC (US) | 2009-07-08 | — | — | EP | disclosed |
| EP-1836173-A2 | ANTI-INFLAMMATORY MEDICAMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20070191336-A1 | p38 kinase inhibitors | DECIPHERA PHARMACEUTICALS, LLC | 2007-08-16 | — | — | US | disclosed |
| US-20070191336-A1 | p38 kinase inhibitors | DECIPHERA PHARMACEUTICALS, LLC | 2007-08-16 | — | — | US | disclosed |
| WO-2006081034-A2 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312349-A1 | ANTI-INFLAMMATORY MEDICAMENTS | ABL2, ABL1, PTK2 | MAPK14 80/4885MAPK13 183/4885MAPK12 118/4885 |
| US-20070191336-A1 | p38 kinase inhibitors | MAPK1, MAP3K8, MAP3K1 | MAPK14 29/4885MAPK13 41/4885MAPK12 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.