Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053615 | 1.00 | EP300 (0.36) | EP300FAAHTP53CYP1A2CYP2C19 | |
| SCHEMBL4381516 | 0.80 | EP300 (0.35) | EP300FAAHTP53CYP1A2CYP2C19 | |
| SCHEMBL4373779 | 0.80 | EP300 (0.35) | EP300FAAHTP53CYP1A2CYP2C19 | |
| Secosubamolide SCHEMBL4051341 | 0.77 | EP300 (0.42) | EP300FAAHTP53CYP1A2CYP2C19 | |
| Secosubamolide SCHEMBL4373980 | 0.77 | EP300 (0.42) | EP300FAAHTP53CYP1A2CYP2C19 | |
| Secosubamolide SCHEMBL29746935 | 0.77 | EP300 (0.42) | EP300FAAHTP53CYP1A2CYP2C19 | |
| SCHEMBL29747018 | 0.77 | EP300 (0.42) | EP300FAAHTP53CYP1A2CYP2C19 | |
| Secokotomolide A SCHEMBL29747263 | 0.77 | EP300 (0.42) | EP300FAAHTP53CYP1A2CYP2C19 | |
| SCHEMBL4052380 | 0.76 | NPC1 (0.40) | EP300FAAHCYP1A2CYP2C19SOAT1 | |
| SCHEMBL4049541 | 0.76 | NPC1 (0.40) | EP300FAAHCYP1A2CYP2C19SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | disclosed |