Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049034 | 0.93 | DPP4 (0.41) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4045384 | 0.92 | DPP4 (0.44) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4044435 | 0.89 | DPP4 (0.47) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4049054 | 0.88 | DPP4 (0.52) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4045804 | 0.88 | DPP4 (0.41) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4045257 | 0.86 | DPP4 (0.44) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4046995 | 0.85 | DPP4 (0.44) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4050902 | 0.83 | DPP4 (0.46) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4052757 | 0.83 | DPP4 (0.48) | DPP4DPP7DPP8DPP9CTSK | |
| SCHEMBL4050245 | 0.83 | DPP4 (0.45) | DPP4DPP7DPP8DPP9CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |