Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.60 |
| ▸ | CNR2 | P34972 | 4/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690535 | 1.00 | CNR1 (0.60) | CNR1CNR2PTGER4KDM4EHTR3A | |
| SCHEMBL4051067 | 0.90 | PTGER4 (0.49) | CNR1CNR2PTGER4CFD | |
| SCHEMBL13690950 | 0.88 | CNR1 (0.70) | CNR1CNR2PTGER4KDM4ECFD | |
| SCHEMBL13690545 | 0.88 | PTGER4 (0.48) | CNR1CNR2PTGER4HTR3AGPR139 | |
| SCHEMBL4058848 | 0.88 | PTGER4 (0.50) | CNR1CNR2PTGER4HTR3APOLB | |
| SCHEMBL13691041 | 0.88 | PTGER4 (0.50) | CNR1CNR2PTGER4HTR3APOLB | |
| SCHEMBL4048491 | 0.80 | CNR1 (0.72) | CNR1CNR2KDM4ECFD | |
| SCHEMBL4049486 | 0.79 | CNR1 (0.51) | CNR1CNR2PTGER4HTR3ACFD | |
| SCHEMBL13691111 | 0.78 | CNR1 (0.70) | CNR1CNR2KDM4ECFD | |
| SCHEMBL4050207 | 0.78 | CNR1 (0.70) | CNR1CNR2KDM4ECFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |