Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.61 |
| ▸ | MAX | P61244 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050936 | 1.00 | MYC (0.61) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4049180 | 0.91 | MYC (0.64) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4049181 | 0.91 | MYC (0.64) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4056474 | 0.90 | HPGD (0.61) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4056471 | 0.90 | HPGD (0.61) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4050895 | 0.84 | MYC (0.53) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4231354 | 0.84 | MYC (0.67) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4231351 | 0.84 | MYC (0.67) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4051796 | 0.83 | MYC (0.66) | MYCMAXMAPTALDH1A1GAA | |
| SCHEMBL4051795 | 0.83 | MYC (0.66) | MYCMAXMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |