Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.52 |
| ▸ | CFD | P00746 | 4/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690955 | 1.00 | CNR1 (0.52) | CNR1CNR2CFDF10NPC1 | |
| SCHEMBL4053696 | 0.88 | CNR1 (0.55) | CNR1CNR2CFDNPC1GAA | |
| SCHEMBL13690593 | 0.86 | CNR1 (0.47) | CNR1CNR2CFDF10HTR3A | |
| SCHEMBL4051161 | 0.86 | CNR1 (0.47) | CNR1CNR2CFDF10HTR3A | |
| SCHEMBL4050207 | 0.85 | CNR1 (0.70) | CNR1CNR2CFDNPC1GAA | |
| SCHEMBL13691111 | 0.85 | CNR1 (0.70) | CNR1CNR2CFDNPC1GAA | |
| SCHEMBL4060702 | 0.85 | CNR1 (0.52) | CNR1CNR2CFDF10GAA | |
| SCHEMBL4059110 | 0.84 | CNR1 (0.49) | CNR1CNR2CFDGAAHTR3A | |
| SCHEMBL4055245 | 0.84 | CNR1 (0.49) | CNR1CNR2GAAHTR3A | |
| SCHEMBL13691011 | 0.84 | CNR1 (0.49) | CNR1CNR2GAAHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |