Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 4/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690828 | 1.00 | CNR1 (0.47) | CNR1ADORA2AADORA1CNR2PTGER4 | |
| SCHEMBL13690978 | 0.95 | CNR1 (0.46) | CNR1ADORA2AADORA1CNR2PTGER4 | |
| SCHEMBL13690591 | 0.92 | CNR1 (0.39) | CNR1CNR2HTR3AHTR4 | |
| SCHEMBL4057564 | 0.92 | CNR1 (0.39) | CNR1CNR2HTR3AHTR4 | |
| SCHEMBL13690636 | 0.91 | CNR1 (0.47) | CNR1ADORA2AADORA1PTGER4MMP1 | |
| SCHEMBL4052469 | 0.91 | CNR1 (0.40) | CNR1CNR2HTR3ASSTR4 | |
| SCHEMBL13691090 | 0.91 | CNR1 (0.38) | CNR1CNR2HTR3ASSTR4 | |
| SCHEMBL13691262 | 0.91 | CNR1 (0.40) | CNR1CNR2HTR3ASSTR4 | |
| SCHEMBL13691004 | 0.91 | CNR1 (0.47) | CNR1ADORA2AADORA1CNR2PTGER4 | |
| SCHEMBL4049851 | 0.91 | CNR1 (0.47) | CNR1ADORA2AADORA1CNR2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |