Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.45 |
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690618 | 0.96 | CNR1 (0.44) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL4051488 | 0.96 | CNR1 (0.44) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL4048845 | 0.93 | CNR1 (0.45) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL13691133 | 0.90 | CNR1 (0.42) | CNR1CNR2SYKKDM4C | |
| SCHEMBL13690594 | 0.90 | CNR1 (0.48) | CNR1CNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL4049921 | 0.90 | CNR1 (0.43) | CNR1CNR2SYKKDM4C | |
| SCHEMBL4051781 | 0.90 | CNR1 (0.43) | CNR1CNR2SYKKDM4C | |
| SCHEMBL4058132 | 0.89 | CNR1 (0.48) | CNR1CNR2SYKKDM4C | |
| SCHEMBL13690621 | 0.89 | CNR1 (0.48) | CNR1CNR2SYKKDM4C | |
| SCHEMBL4230815 | 0.89 | CNR1 (0.44) | CNR1CNR2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |