Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13765252 | 0.89 | CYSLTR2 (0.32) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4054649 | 0.89 | CYSLTR2 (0.32) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4054644 | 0.89 | CYSLTR2 (0.32) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4059512 | 0.86 | CYSLTR2 (0.33) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4059510 | 0.86 | CYSLTR2 (0.33) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL14159715 | 0.83 | ALOX5AP (0.34) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4053022 | 0.83 | CYSLTR2 (0.33) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4053023 | 0.83 | CYSLTR2 (0.33) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4058907 | 0.83 | CYSLTR2 (0.35) | CYSLTR2CYSLTR1ALOX5AP | |
| SCHEMBL4052136 | 0.82 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |