Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 7/20 | 0.43 |
| ▸ | CFD | P00746 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690997 | 0.90 | CNR1 (0.49) | CNR1CNR2HTR3ACFD | |
| SCHEMBL4052972 | 0.90 | CNR1 (0.49) | CNR1CNR2HTR3ACFD | |
| SCHEMBL4048224 | 0.89 | CNR1 (0.47) | CNR1CNR2HTR3ACFDMEN1 | |
| SCHEMBL4049459 | 0.87 | CNR1 (0.48) | CNR1CNR2HTR3ACFDHTR3E | |
| SCHEMBL13691012 | 0.87 | CNR1 (0.48) | CNR1CNR2HTR3ACFDHTR3E | |
| SCHEMBL13690593 | 0.86 | CNR1 (0.47) | CNR1CNR2HTR3ACFDMEN1 | |
| SCHEMBL4051161 | 0.86 | CNR1 (0.47) | CNR1CNR2HTR3ACFDMEN1 | |
| SCHEMBL4050611 | 0.85 | CNR1 (0.63) | CNR1CNR2HTR3AHTR4 | |
| SCHEMBL13691030 | 0.85 | CNR1 (0.63) | CNR1CNR2HTR3AHTR4 | |
| SCHEMBL4054508 | 0.85 | CNR1 (0.63) | CNR1CNR2HTR3AHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |