Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.65 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.45 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.45 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.45 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690930 | 0.87 | CNR1 (0.62) | CNR1CNR2ACHEHTR3APTGER4 | |
| SCHEMBL4055563 | 0.84 | CNR1 (0.66) | CNR1CNR2ACHEHTR3APTGER4 | |
| SCHEMBL4057063 | 0.84 | CNR1 (0.74) | CNR1CNR2ACHEHTR3AROCK2 | |
| SCHEMBL13690933 | 0.83 | CNR1 (0.69) | CNR1CNR2ACHEHTR3AROCK2 | |
| SCHEMBL4052817 | 0.83 | CNR1 (0.69) | CNR1CNR2ACHEHTR3AROCK2 | |
| SCHEMBL4049800 | 0.83 | CNR1 (0.69) | CNR1CNR2ACHEHTR3AROCK2 | |
| SCHEMBL4560432 | 0.82 | CNR1 (0.83) | CNR1CNR2ACHEHTR3AROCK2 | |
| SCHEMBL30641081 | 0.81 | CNR1 (0.70) | CNR1CNR2ACHEHTR3APTGER4 | |
| SCHEMBL13690923 | 0.81 | CNR1 (0.70) | CNR1CNR2ACHEHTR3APTGER4 | |
| SCHEMBL4050989 | 0.81 | CNR1 (0.70) | CNR1CNR2ACHEHTR3APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |