Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100664 | 0.81 | KMT2A (1.00) | KDM4EMAPTMEN1HPGDKMT2A | |
| SCHEMBL4741962 | 0.81 | EGFR (0.58) | KDM4ELMNAMAPTMEN1HPGD | |
| SCHEMBL6265421 | 0.79 | MAPT (1.00) | KDM4ELMNAMAPTMEN1HPGD | |
| SCHEMBL13943678 | 0.78 | KMT2A (0.93) | KDM4EMAPTMEN1HPGDKMT2A | |
| SCHEMBL16363393 | 0.77 | HAVCR2 (1.00) | KDM4ELMNAMAPTMEN1HPGD | |
| SCHEMBL13100621 | 0.76 | KMT2A (0.89) | KDM4ELMNAMAPTMEN1HPGD | |
| SCHEMBL13943708 | 0.76 | MEN1 (0.81) | KDM4EMAPTMEN1HPGDKMT2A | |
| SCHEMBL29110517 | 0.76 | MAPT (0.57) | KDM4ELMNAMAPTMEN1HPGD | |
| SCHEMBL29771431 | 0.76 | MAPT (0.57) | KDM4ELMNAMAPTMEN1HPGD | |
| SCHEMBL15452549 | 0.76 | KMT2A (0.87) | KDM4EMAPTMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009029617-A1 | DIARYLAMINE-SUBSTITUTED QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |