Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056114 | 0.86 | ADRB3 (0.36) | MEN1KMT2APTPN1ALOX5ADRB3 | |
| SCHEMBL4048869 | 0.85 | PTPN1 (0.43) | MEN1KMT2APTPN1ALOX5 | |
| SCHEMBL4048872 | 0.85 | PTPN1 (0.43) | MEN1KMT2APTPN1ALOX5 | |
| SCHEMBL4059792 | 0.84 | PTPN1 (0.42) | MEN1KMT2APTPN1ALOX5 | |
| SCHEMBL4059795 | 0.84 | PTPN1 (0.42) | MEN1KMT2APTPN1MAPTALDH1A1 | |
| SCHEMBL4054738 | 0.84 | PTPN1 (0.42) | MEN1KMT2APTPN1ALOX5 | |
| SCHEMBL4054740 | 0.84 | PTPN1 (0.42) | MEN1KMT2APTPN1ALOX5 | |
| SCHEMBL4052695 | 0.80 | MEN1 (0.34) | MEN1KMT2ANPC1RAB9APTPN1 | |
| SCHEMBL4052690 | 0.80 | MEN1 (0.34) | MEN1KMT2ANPC1RAB9APTPN1 | |
| SCHEMBL4054938 | 0.77 | KMT2A (0.40) | MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |