Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.69 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.69 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23381156 | 1.00 | TLR7 (0.69) | TLR7TLR8NUDT1 | |
| SCHEMBL23381089 | 1.00 | TLR7 (0.69) | TLR7TLR8NUDT1 | |
| SCHEMBL893024 | 0.90 | TLR7 (0.74) | TLR7TLR8NUDT1 | |
| SCHEMBL29977522 | 0.90 | TLR7 (0.74) | TLR7TLR8NUDT1 | |
| SCHEMBL23381070 | 0.88 | TLR7 (0.72) | TLR7TLR8NUDT1 | |
| SCHEMBL23360872 | 0.88 | TLR7 (0.72) | TLR7TLR8NUDT1 | |
| SCHEMBL29825771 | 0.88 | TLR7 (0.72) | TLR7TLR8NUDT1 | |
| SCHEMBL23381040 | 0.88 | TLR7 (0.72) | TLR7TLR8NUDT1 | |
| SCHEMBL23380991 | 0.86 | TLR7 (0.62) | TLR7TLR8NUDT1 | |
| SCHEMBL18179117 | 0.85 | TLR7 (0.76) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599726-A4 | SELECTIVE MODULATION OF TLR-MEDIATED BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES CO (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1567155-A4 | ADMINISTRATION OF DENDRITIC CELLS PARTIALLY MATURED IN VITRO FOR THE TREATMENT OF TUMORS | NORTHWEST BIOTHERAPEUTICS INC (US) | 2006-12-13 | — | — | EP | disclosed |
| EP-1599726-A2 | SELECTIVE MODULATION OF TLR-MEDIATED BIOLOGICAL ACTIVITY | 3M Innovative Properties Company (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1567155-A2 | ADMINISTRATION OF DENDRITIC CELLS PARTIALLY MATURED IN VITRO FOR THE TREATMENT OF TUMORS | NorthWest Biotherapeutics, Inc. (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004075865-A2 | SELECTIVE MODULATION OF TLR-MEDIATED BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004053072-A2 | ADMINISTRATION OF DENDRITIC CELLS PARTIALLY MATURED IN VITRO FOR THE TREATMENT OF TUMORS | NORTHWEST BIOTHERAPEUTICS, INC. (US) | 2004-06-24 | — | — | WO | disclosed |