Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.34 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054597 | 1.00 | CYSLTR1 (0.38) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL13765251 | 0.94 | CYSLTR1 (0.39) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL5332207 | 0.90 | CYSLTR1 (0.41) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL5332200 | 0.90 | CYSLTR1 (0.41) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL4049713 | 0.87 | CYSLTR1 (0.39) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL4049710 | 0.87 | CYSLTR1 (0.39) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL4055234 | 0.87 | CYSLTR1 (0.38) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL4055232 | 0.87 | CYSLTR1 (0.38) | CYSLTR1CYSLTR2ABCC1MEN1ABCC3 | |
| SCHEMBL4060340 | 0.86 | CYSLTR1 (0.37) | CYSLTR1CYSLTR2MEN1ABCB11KMT2A | |
| SCHEMBL13765250 | 0.86 | CYSLTR1 (0.37) | CYSLTR1CYSLTR2MEN1ABCB11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |
| US-7557212-B2 | Tricyclic derivatives as LTD4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2009-07-07 | — | — | US | disclosed |