Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054715 | 1.00 | HSD17B3 (0.61) | HSD17B3 | |
| SCHEMBL4047899 | 0.92 | HSD17B3 (0.70) | HSD17B3 | |
| SCHEMBL4047894 | 0.92 | HSD17B3 (0.70) | HSD17B3 | |
| SCHEMBL4046414 | 0.87 | HSD17B3 (0.60) | HSD17B3 | |
| SCHEMBL4046406 | 0.87 | HSD17B3 (0.60) | HSD17B3 | |
| SCHEMBL4055997 | 0.87 | HSD17B3 (0.60) | HSD17B3 | |
| SCHEMBL4056001 | 0.87 | HSD17B3 (0.60) | HSD17B3 | |
| SCHEMBL4800262 | 0.85 | HSD17B3 (0.67) | HSD17B3 | |
| SCHEMBL4800268 | 0.85 | HSD17B3 (0.67) | HSD17B3 | |
| SCHEMBL6025559 | 0.84 | HSD17B3 (0.55) | HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720613-A4 | FUSED TRICYCLIC COMPOUNDS AS INHIBITORS OF 17BETA-HYDROXYSTEROID DEHYDROGERNASE 3 | BRISTOL MYERS SQUIBB CO (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1720613-A2 | FUSED TRICYCLIC COMPOUNDS AS INHIBITORS OF 17BETA-HYDROXYSTEROID DEHYDROGERNASE 3 | Bristol-Myers Squibb Company (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005084296-A2 | FUSED TRICYCLIC COMPOUNDS AS INHIBITORS OF 17BETA-HYDROXYSTEROID DEHYDROGERNASE 3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-15 | — | — | WO | disclosed |