Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.48 |
| ▸ | CNR2 | P34972 | 9/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055740 | 0.91 | CNR1 (0.49) | CNR1CNR2CTSLCTSSCTSV | |
| SCHEMBL13690525 | 0.91 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL4049369 | 0.90 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL4056091 | 0.90 | CNR1 (0.59) | CNR1CNR2 | |
| SCHEMBL4049934 | 0.89 | CNR1 (0.45) | CNR1CNR2CTSLCTSSCTSV | |
| SCHEMBL13691236 | 0.89 | CNR1 (0.44) | CNR1CNR2CTSLCTSSCTSV | |
| SCHEMBL4056713 | 0.89 | CNR1 (0.44) | CNR1CNR2CTSLCTSSCTSV | |
| SCHEMBL4053834 | 0.88 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL4059339 | 0.88 | CNR1 (0.62) | CNR1CNR2 | |
| SCHEMBL4051609 | 0.87 | CNR1 (0.48) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |