Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.52 |
| ▸ | CNR2 | P34972 | 4/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | CFD | P00746 | 6/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691023 | 1.00 | CNR1 (0.52) | CNR1CNR2PTGER4CFDELANE | |
| SCHEMBL4053737 | 0.93 | CNR1 (0.55) | CNR1CNR2PTGER4CFD | |
| SCHEMBL13690632 | 0.92 | CNR1 (0.53) | CNR1CNR2PTGER4CFD | |
| SCHEMBL4049486 | 0.92 | CNR1 (0.51) | CNR1CNR2PTGER4CFDHTR3A | |
| SCHEMBL13690991 | 0.92 | CNR1 (0.51) | CNR1CNR2PTGER4CFD | |
| SCHEMBL4051067 | 0.89 | PTGER4 (0.49) | CNR1CNR2PTGER4CFD | |
| SCHEMBL4055410 | 0.89 | CNR1 (0.50) | CNR1CNR2PTGER4CFDELANE | |
| SCHEMBL13691011 | 0.89 | CNR1 (0.49) | CNR1CNR2PTGER4ELANEGAA | |
| SCHEMBL4055245 | 0.89 | CNR1 (0.49) | CNR1CNR2PTGER4ELANEGAA | |
| SCHEMBL12885060 | 0.88 | CNR1 (0.67) | CNR1CNR2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |