Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 7/20 | 0.45 |
| ▸ | MMP2 | P08253 | 6/20 | 0.42 |
| ▸ | MMP3 | P08254 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051967 | 0.90 | CNR1 (0.51) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL13690582 | 0.90 | CNR1 (0.51) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL13691008 | 0.89 | CNR1 (0.64) | CNR1CNR2HTR3ACFD | |
| SCHEMBL4049459 | 0.89 | CNR1 (0.48) | CNR1CNR2HTR3AF10CFD | |
| SCHEMBL13691012 | 0.89 | CNR1 (0.48) | CNR1CNR2HTR3AF10CFD | |
| SCHEMBL4048901 | 0.88 | CNR1 (0.65) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL4050767 | 0.88 | CNR1 (0.65) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL4049353 | 0.88 | CNR1 (0.51) | CNR1CNR2HTR3ACFD | |
| SCHEMBL4053493 | 0.86 | CNR1 (0.49) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL13690544 | 0.86 | CNR1 (0.49) | CNR1CNR2HTR3AMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |