Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.83 |
| ▸ | DUSP26 | Q9BV47 | 3/20 | 0.56 |
| ▸ | ACP1 | P24666 | 6/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056339 | 1.00 | PTPN1 (0.83) | PTPN1DUSP26ACP1PTPN2ITGB3 | |
| SCHEMBL13689596 | 1.00 | PTPN1 (0.83) | PTPN1DUSP26ACP1PTPN2ITGB3 | |
| SCHEMBL4056110 | 0.92 | PTPN1 (0.83) | PTPN1DUSP26ACP1PTPN2ITGB3 | |
| SCHEMBL4056109 | 0.92 | PTPN1 (0.83) | PTPN1DUSP26ACP1PTPN2ITGB3 | |
| SCHEMBL4053602 | 0.89 | PTPN1 (0.80) | PTPN1DUSP26ACP1PTPN2ITGB3 | |
| SCHEMBL13689587 | 0.89 | PTPN1 (0.80) | PTPN1DUSP26ACP1PTPN2ITGB3 | |
| SCHEMBL4053603 | 0.89 | PTPN1 (0.80) | PTPN1DUSP26ACP1PTPN2ITGB3 | |
| SCHEMBL4053688 | 0.88 | PTPN1 (0.81) | PTPN1DUSP26ACP1PTPN2AURKA | |
| SCHEMBL4053691 | 0.88 | PTPN1 (0.81) | PTPN1DUSP26ACP1PTPN2AURKA | |
| SCHEMBL13689583 | 0.88 | PTPN1 (0.81) | PTPN1DUSP26ACP1PTPN2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |