Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691009 | 1.00 | CNR1 (0.41) | CNR1CNR2HTR4CYP3A4SLC2A1 | |
| SCHEMBL4051582 | 0.93 | CNR1 (0.42) | CNR1CNR2HTR4CYP3A4SLC2A1 | |
| SCHEMBL4058325 | 0.92 | CNR1 (0.42) | CNR1CNR2HTR4CYP3A4HTR3A | |
| SCHEMBL4059674 | 0.92 | CNR1 (0.41) | CNR1CNR2HTR4CYP3A4SLC2A1 | |
| SCHEMBL13691020 | 0.92 | CNR1 (0.42) | CNR1CNR2HTR4CYP3A4HTR3A | |
| SCHEMBL13690954 | 0.92 | CNR1 (0.41) | CNR1CNR2HTR4CYP3A4SLC2A1 | |
| SCHEMBL13691004 | 0.92 | CNR1 (0.47) | CNR1CNR2HTR4SSTR4 | |
| SCHEMBL4049851 | 0.92 | CNR1 (0.47) | CNR1CNR2HTR4SSTR4 | |
| SCHEMBL13690665 | 0.91 | CNR1 (0.41) | CNR1CNR2HTR4CYP3A4SLC2A1 | |
| SCHEMBL13690591 | 0.91 | CNR1 (0.39) | CNR1CNR2HTR4CYP3A4GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |