SCHEMBL4056586

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4052345	0.92	PIK3CA (0.52)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4
	SCHEMBL4055900	0.90	PIK3CA (0.59)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4
	SCHEMBL4058369	0.90	PIK3CD (0.54)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4
	SCHEMBL4057904	0.90	PIK3CA (0.52)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4
	SCHEMBL4053671	0.89	PIK3CA (0.55)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4
	SCHEMBL4060794	0.89	PIK3CA (0.55)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4
	SCHEMBL4054844	0.89	PIK3CA (0.51)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4
	SCHEMBL4054314	0.89	PIK3CA (0.55)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4
	SCHEMBL4063804	0.89	PIK3CA (0.55)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4
	SCHEMBL3514618	0.88	PIK3CA (0.49)	PIK3CAPIK3CDPIK3CBPIK3CGBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.