Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.67 |
| ▸ | CNR2 | P34972 | 4/20 | 0.52 |
| ▸ | MMP1 | P03956 | 6/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048901 | 0.91 | CNR1 (0.65) | CNR1CNR2HTR4ROCK2ACHE | |
| SCHEMBL4050767 | 0.91 | CNR1 (0.65) | CNR1CNR2HTR4ROCK2ACHE | |
| SCHEMBL4050497 | 0.90 | CNR1 (0.69) | CNR1CNR2HTR4ROCK2ACHE | |
| SCHEMBL13690922 | 0.90 | CNR1 (0.69) | CNR1CNR2HTR4ROCK2ACHE | |
| SCHEMBL4053063 | 0.89 | CNR1 (0.77) | CNR1CNR2HTR4ROCK2ACHE | |
| SCHEMBL29993194 | 0.89 | CNR1 (0.77) | CNR1CNR2HTR4ROCK2ACHE | |
| SCHEMBL30473233 | 0.89 | CNR1 (0.77) | CNR1CNR2HTR4ROCK2ACHE | |
| SCHEMBL4050611 | 0.89 | CNR1 (0.63) | CNR1CNR2HTR4ROCK2ACHE | |
| SCHEMBL4049454 | 0.89 | CNR1 (0.63) | CNR1CNR2HTR4ROCK2ACHE | |
| SCHEMBL13691030 | 0.89 | CNR1 (0.63) | CNR1CNR2HTR4ROCK2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |