SCHEMBL4056773

SCHEMBL4056773

O=S1(=O)N(CCCC2CO2)c2ccccc2N1c1ccccc1F

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 20/20 0.64
SLC6A4 P31645 13/20 0.64
SLC6A3 Q01959 10/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4942700 0.92 SLC6A2 (0.73) SLC6A2SLC6A4SLC6A3
SCHEMBL13799145 0.92 SLC6A2 (0.73) SLC6A2SLC6A4SLC6A3
SCHEMBL4066474 0.82 SLC6A2 (0.63) SLC6A2SLC6A4SLC6A3
SCHEMBL4055043 0.82 SLC6A2 (0.65) SLC6A2SLC6A4SLC6A3
SCHEMBL4062019 0.82 SLC6A2 (0.76) SLC6A2SLC6A4SLC6A3
SCHEMBL4057467 0.80 SLC6A2 (0.71) SLC6A2SLC6A4SLC6A3
SCHEMBL14161176 0.79 SLC6A2 (0.73) SLC6A2SLC6A4SLC6A3
SCHEMBL4065517 0.79 SLC6A2 (0.71) SLC6A2SLC6A4SLC6A3
SCHEMBL3602822 0.79 SLC6A2 (0.69) SLC6A2SLC6A4SLC6A3
SCHEMBL4942613 0.78 SLC6A2 (0.56) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2061776-A1 ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE Wyeth a Corporation of the State of Delaware (US) 2009-05-27 EP disclosed
WO-2008073459-A1 ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE WYETH (US) 2008-06-19 WO disclosed