Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.81 |
| ▸ | DUSP26 | Q9BV47 | 3/20 | 0.58 |
| ▸ | ACP1 | P24666 | 4/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 3/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056778 | 1.00 | PTPN1 (0.81) | PTPN1DUSP26ACP1PTPN2NPC1 | |
| SCHEMBL4049740 | 0.87 | PTPN1 (0.61) | PTPN1DUSP26ITGB3ITGAVAURKA | |
| SCHEMBL4049736 | 0.87 | PTPN1 (0.61) | PTPN1DUSP26ITGB3ITGAVAURKA | |
| SCHEMBL4051102 | 0.86 | DUSP26 (0.61) | PTPN1DUSP26ACP1PTPN2NPC1 | |
| SCHEMBL4058782 | 0.86 | DUSP26 (0.61) | PTPN1DUSP26ACP1PTPN2NPC1 | |
| SCHEMBL4051099 | 0.86 | DUSP26 (0.61) | PTPN1DUSP26ACP1PTPN2NPC1 | |
| SCHEMBL4058785 | 0.86 | DUSP26 (0.61) | PTPN1DUSP26ACP1PTPN2NPC1 | |
| SCHEMBL4051528 | 0.84 | PTPN1 (0.78) | PTPN1DUSP26ACP1PTPN2ITGB3 | |
| SCHEMBL4051524 | 0.84 | PTPN1 (0.78) | PTPN1DUSP26ACP1PTPN2ITGB3 | |
| SCHEMBL4056339 | 0.84 | PTPN1 (0.83) | PTPN1DUSP26ACP1PTPN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |