SCHEMBL4056941

SCHEMBL4056941

CCCCc1oc(-c2ccc(OC(F)(F)F)cc2)nc1CCOc1cccc(CC(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.48
PPARA Q07869 18/20 0.48
PPARD Q03181 4/20 0.47
PLA2G4B P0C869 1/20 0.47
PTPN11 Q06124 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4064926 0.95 PPARG (0.53) PPARGPPARAPPARD
SCHEMBL4394323 0.87 PPARG (0.61) PPARGPPARAPPARD
SCHEMBL4057835 0.87 PPARG (0.45) PPARGPPARAPPARD
SCHEMBL5682552 0.86 PPARG (0.46) PPARGPPARAPPARD
SCHEMBL4062648 0.85 PPARG (0.54) PPARGPPARAPPARD
SCHEMBL4059413 0.84 PPARG (0.50) PPARGPPARAPPARD
SCHEMBL4065023 0.81 PPARA (0.46) PPARGPPARAPPARD
SCHEMBL4391022 0.81 PPARG (0.61) PPARGPPARA
SCHEMBL4393324 0.81 PPARG (0.64) PPARGPPARAPPARD
SCHEMBL4391062 0.80 PPARG (0.61) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1666472-B1 PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE ONO PHARMACEUTICAL CO (JP) 2012-08-01 EP disclosed
US-7560475-B2 Phenylacetic acid derivative, process for producing the same, and use ONO PHARMACEUTICAL CO., LTD. (JP) 2009-07-14 US disclosed
US-20070105868-A1 Phenylacetic acid derivative, process for producing the same, and use ONO PHARMACEUTICAL CO., LTD. (JP) 2007-05-10 US disclosed
EP-1666472-A1 PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE ONO PHARMACEUTICAL CO., LTD. (JP) 2006-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105868-A1 Phenylacetic acid derivative, process for producing the same, and use PPARA, PPARD, PPARG PPARG 3/4885PPARA 1/4885PPARD 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.