Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | XDH | P47989 | 4/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319165 | 0.89 | MAOB (0.49) | MAOBXDHFNTAFNTBPGGT1B | |
| SCHEMBL2700393 | 0.88 | MAOB (0.56) | MAOBXDHFNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL4488053 | 0.87 | MAOB (0.55) | MAOBXDHFNTAFNTBPGGT1B | |
| SCHEMBL8807037 | 0.82 | MAOB (0.60) | MAOBXDHGAAMAPTMAOA | |
| SCHEMBL3788705 | 0.81 | MAPT (0.54) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL3317611 | 0.79 | FNTA (0.54) | MAOBXDHFNTAFNTBPGGT1B | |
| SCHEMBL6484493 | 0.78 | FNTA (0.58) | MAOBXDHFNTAFNTBPGGT1B | |
| SCHEMBL3865512 | 0.78 | MAOB (0.77) | MAOBXDHFNTAFNTBPGGT1B | |
| SCHEMBL3786669 | 0.78 | MAOB (0.54) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL28185508 | 0.78 | MAOB (0.58) | MAOBXDHFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824825-A4 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INT INC (BB) | 2009-07-08 | — | — | EP | disclosed |
| EP-1824825-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | Medicure International Inc. (BB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006045203-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-04 | — | — | WO | disclosed |