Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 9/20 | 0.47 |
| ▸ | DUSP26 | Q9BV47 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057740 | 1.00 | PTPN1 (0.54) | PTPN1AURKADUSP26MGAMCA12 | |
| SCHEMBL4050789 | 0.90 | PTPN1 (0.58) | PTPN1AURKADUSP26MGAMCA12 | |
| SCHEMBL4060687 | 0.85 | PTPN1 (0.73) | PTPN1AURKADUSP26MGAMCA12 | |
| SCHEMBL4060684 | 0.85 | PTPN1 (0.73) | PTPN1AURKADUSP26MGAMCA12 | |
| SCHEMBL4050794 | 0.83 | PTPN1 (0.62) | PTPN1AURKADUSP26MGAMCA12 | |
| SCHEMBL4053754 | 0.83 | PTPN1 (0.68) | PTPN1AURKADUSP26MGAMCA12 | |
| SCHEMBL4053753 | 0.83 | PTPN1 (0.68) | PTPN1AURKADUSP26MGAMCA12 | |
| SCHEMBL4056961 | 0.82 | PTPN1 (0.60) | PTPN1AURKADUSP26MGAMCA12 | |
| SCHEMBL4049524 | 0.80 | PTPN1 (0.73) | PTPN1AURKADUSP26MGAMCA12 | |
| SCHEMBL4049525 | 0.80 | PTPN1 (0.73) | PTPN1AURKADUSP26MGAMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |