Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.76 |
| ▸ | DUSP26 | Q9BV47 | 3/20 | 0.62 |
| ▸ | AURKA | O14965 | 9/20 | 0.61 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.57 |
| ▸ | INCENP | Q9NQS7 | 6/20 | 0.57 |
| ▸ | ACP1 | P24666 | 3/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057081 | 1.00 | PTPN1 (0.76) | PTPN1DUSP26AURKAAURKBINCENP | |
| SCHEMBL4048414 | 0.92 | PTPN1 (0.75) | PTPN1DUSP26AURKAACP1PTPN2 | |
| SCHEMBL4053756 | 0.91 | PTPN1 (0.72) | PTPN1DUSP26AURKAAURKBINCENP | |
| SCHEMBL4056644 | 0.91 | PTPN1 (0.71) | PTPN1DUSP26AURKAAURKBINCENP | |
| SCHEMBL4060600 | 0.91 | PTPN1 (0.71) | PTPN1DUSP26AURKAAURKBINCENP | |
| SCHEMBL4056648 | 0.91 | PTPN1 (0.71) | PTPN1DUSP26AURKAAURKBINCENP | |
| SCHEMBL4060603 | 0.91 | PTPN1 (0.71) | PTPN1DUSP26AURKAAURKBINCENP | |
| SCHEMBL4049524 | 0.90 | PTPN1 (0.73) | PTPN1DUSP26AURKAAURKBINCENP | |
| SCHEMBL4060687 | 0.90 | PTPN1 (0.73) | PTPN1DUSP26AURKAAURKBINCENP | |
| SCHEMBL4225045 | 0.90 | PTPN1 (0.73) | PTPN1DUSP26AURKAAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |