Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BID | P55957 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206588 | 0.95 | CYP2D6 (0.40) | CYP2D6KCNH2SOAT2SOAT1EPHX2 | |
| SCHEMBL5204826 | 0.93 | CYP2D6 (0.42) | CYP2D6KCNH2SOAT2SOAT1EPHX2 | |
| SCHEMBL5207401 | 0.93 | CYP2D6 (0.42) | CYP2D6KCNH2SOAT2SOAT1EPHX2 | |
| SCHEMBL5206574 | 0.93 | CYP2D6 (0.42) | CYP2D6KCNH2SOAT2SOAT1EPHX2 | |
| SCHEMBL5207708 | 0.93 | CYP2D6 (0.42) | CYP2D6KCNH2SOAT2SOAT1EPHX2 | |
| SCHEMBL5207917 | 0.93 | CYP2D6 (0.42) | CYP2D6KCNH2SOAT2SOAT1EPHX2 | |
| SCHEMBL5209886 | 0.93 | CYP2D6 (0.42) | CYP2D6KCNH2SOAT2SOAT1EPHX2 | |
| SCHEMBL5207240 | 0.93 | CYP2D6 (0.42) | CYP2D6KCNH2SOAT2SOAT1EPHX2 | |
| SCHEMBL5207398 | 0.93 | CYP2D6 (0.42) | CYP2D6KCNH2SOAT2SOAT1EPHX2 | |
| SCHEMBL613044 | 0.89 | TLR8 (0.33) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465010-B1 | Positive resist composition | FUJIFILM CORP (JP) | 2009-10-21 | — | — | EP | disclosed |
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-7232640-B1 | Positive resist composition | FUJIFILM CORPORATION (JP) | 2007-06-19 | — | — | US | disclosed |
| US-20070128547-A1 | POSITIVE RESIST COMPOSITION | FUJI PHOTO FILM CO., LTD. | 2007-06-07 | — | — | US | disclosed |
| EP-1465010-A1 | Positive resist composition | FUJI PHOTO FILM CO., LTD. (JP) | 2004-10-06 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |