SCHEMBL4057599

SCHEMBL4057599

Cc1ccc(CC(=O)O)cc1OCCc1nc(-c2ccc(-c3ccoc3)cc2)oc1C

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.46
PPARG P37231 18/20 0.46
PPARD Q03181 3/20 0.45
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11960916 0.91 MAPT (0.43) PPARAPPARGPPARD
SCHEMBL4063766 0.89 PPARG (0.58) PPARAPPARGPPARDKDM4E
SCHEMBL4064554 0.89 PPARA (0.55) PPARAPPARGPPARDKDM4E
SCHEMBL4057606 0.87 PPARA (0.56) PPARAPPARGPPARDKDM4E
SCHEMBL4058695 0.87 PPARG (0.54) PPARAPPARGPPARDKDM4E
SCHEMBL4061925 0.84 PPARG (0.52) PPARAPPARGPPARD
SCHEMBL4060571 0.84 PPARG (0.48) PPARAPPARGPPARDKDM4E
SCHEMBL4056877 0.84 PPARG (0.53) PPARAPPARGPPARD
SCHEMBL5682561 0.83 PPARG (0.47) PPARAPPARGPPARD
SCHEMBL4054929 0.83 PPARG (0.50) PPARAPPARGPPARDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1666472-B1 PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE ONO PHARMACEUTICAL CO (JP) 2012-08-01 EP disclosed
US-7560475-B2 Phenylacetic acid derivative, process for producing the same, and use ONO PHARMACEUTICAL CO., LTD. (JP) 2009-07-14 US disclosed
US-20070105868-A1 Phenylacetic acid derivative, process for producing the same, and use ONO PHARMACEUTICAL CO., LTD. (JP) 2007-05-10 US disclosed
EP-1666472-A1 PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE ONO PHARMACEUTICAL CO., LTD. (JP) 2006-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105868-A1 Phenylacetic acid derivative, process for producing the same, and use PPARA, PPARD, PPARG PPARA 1/4885PPARG 3/4885PPARD 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.