SCHEMBL405887

SCHEMBL405887

C#CC([O])=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529780 0.70
SCHEMBL497542 0.70
Bicarbonate SCHEMBL631216 0.70
Propiolic Acid SCHEMBL4192977 0.70 CA1 (0.36)
Propiolic Acid SCHEMBL1077 0.70
Propiolic Acid SCHEMBL1569415 0.67
SCHEMBL6721949 0.67
Propiolic Acid SCHEMBL18047804 0.67
Bicarbonate SCHEMBL165021 0.67
SCHEMBL15662481 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3130594-B1 PHOSPHONATES OF ACETYLENIC BETULIN DERIVATIVES WITH ANTICANCER ACTIVITY, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION SLASKI UNIV MEDYCZNY W KATOWICACH (PL) 2020-11-11 EP claimed
EP-3130594-A1 PHOSPHONATES OF ACETYLENIC BETULIN DERIVATIVES WITH ANTICANCER ACTIVITY, METHOD FOR THEIR PRODUCTION AND THEIR APPLICATION Slaski Uniwersytet Medyczny w Katowicach (PL) 2017-02-15 EP claimed
EP-1790639-B1 SPIROCYCLIC COMPOUNDS AND THEIR USE AS CXCR4-ANTAGONISTS ONO PHARMACEUTICAL CO (JP) 2014-03-26 EP claimed
US-7951816-B2 Compound containing basic group and use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2011-05-31 US claimed
EP-3957627-B1 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SHIONOGI & CO (JP) 2024-06-19 EP disclosed
EP-4371979-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2024-05-22 EP disclosed
CN-111801330-B Fused ring compounds having dopamine D3 receptor antagonism 盐野义制药株式会社 2024-04-05 CN disclosed
CN-117693500-A Carboxamide derivative and agricultural/horticultural plant disease control agent 组合化学工业株式会社 2024-03-12 CN disclosed
US-11911749-B2 Chromium catalyst precursor, ethylene oligomerization catalyst including the same, and method of preparing ethylene oligomer SK INNOVATION CO., LTD. (KR) 2024-02-27 US disclosed
US-11897899-B2 Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect SHIONOGI & CO., LTD. (JP) 2024-02-13 US disclosed
EP-3466988-B1 OLIGOMERIZING CATALYST AND METHOD FOR PREPARING ETHYLENE OLIGOMER USING SAME SK INNOVATION CO LTD (KR) 2023-11-29 EP disclosed
EP-3495363-B1 NITROGEN-CONTAINING CONDENSED RING COMPOUNDS HAVING DOPAMINE D3 RECEPTOR ANTAGONISTIC EFFECT SHIONOGI & CO (JP) 2023-08-23 EP disclosed
US-4605758-A Preparation of α-arylalkanoic acids SYNTEX PHARMACEUTICALS INTERNATIONAL LTD. (BM) 1986-08-12 US disclosed
EP-0081993-A2 Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1983-06-22 EP disclosed
US-4296199-A CONTAINING A CYAN COLOR FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-10-20 US disclosed
US-4296200-A CONTAINING A COLORLESS CYAN COLOR FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-10-20 US disclosed
US-4264722-A A COLORLESS CYAN-COLOR-FORMING COUPLER COMPRISING 4-OXY-DERIVATIVES OF 1-HYDROXY-2-SEC-AMIDO-NAPHTHALENE OR BENZENE FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
EP-0024033-A1 Photographic colour couplers and light-sensitive material containing them FUJI PHOTO FILM CO., LTD. (JP) 1981-02-18 EP disclosed
US-4207111-A COUPLERS CAPABLE OF FORMING AZOMETHINE DYES ON COUPLING WITH OXIDATION PRODUCT OF AROMATIC PRUMARY AMINE DEVELOPER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-06-10 US disclosed
US-4140532-A ORGANIC SILVER SALT, CATALYST, REDUCING AGENT, 2H-1,3-BENZOTHIAZIN-2,4(3H-)DIONE FUJI PHOTO FILM CO., LTD. (JP) 1979-02-20 US disclosed