Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 6/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.41 |
| ▸ | CFD | P00746 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691042 | 1.00 | CNR1 (0.48) | CNR1CNR2HTR3AF10HTR4 | |
| SCHEMBL13690544 | 0.91 | CNR1 (0.49) | CNR1CNR2HTR3AF10HTR4 | |
| SCHEMBL4053493 | 0.91 | CNR1 (0.49) | CNR1CNR2HTR3AF10HTR4 | |
| SCHEMBL13691037 | 0.88 | CNR1 (0.63) | CNR1CNR2HTR3ACFD | |
| SCHEMBL13691043 | 0.87 | CNR1 (0.47) | CNR1CNR2HTR3AF10CFD | |
| SCHEMBL13691045 | 0.86 | CNR1 (0.51) | CNR1CNR2HTR3ACFD | |
| SCHEMBL4047866 | 0.86 | CNR1 (0.51) | CNR1CNR2HTR3ACFD | |
| SCHEMBL13690945 | 0.83 | CNR1 (0.52) | CNR1CNR2HTR3AF10HTR4 | |
| SCHEMBL4060702 | 0.83 | CNR1 (0.52) | CNR1CNR2HTR3AF10HTR4 | |
| SCHEMBL4051967 | 0.82 | CNR1 (0.51) | CNR1CNR2HTR3AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |