Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045536 | 0.80 | NOTUM (0.39) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL1041682 | 0.80 | EPHX2 (0.43) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL30451893 | 0.80 | EPHX2 (0.43) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL14937673 | 0.77 | KDM4E (0.45) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL3923371 | 0.76 | IDO1 (0.56) | NOTUMIDO1 | |
| SCHEMBL14310879 | 0.76 | AR (0.40) | NOTUMIDO1TAS2R14PDE3BPDE3A | |
| SCHEMBL1129534 | 0.76 | MEN1 (0.44) | MAPTMEN1KMT2ALMNATAS2R14 | |
| SCHEMBL2098125 | 0.76 | MAPT (0.38) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2095511 | 0.76 | MAPT (0.38) | NOTUMMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2098124 | 0.76 | AR (0.39) | NOTUMMAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032537-A1 | NEW UREA DERIVATIVES AND THE APPLICATION THEREOF | ScheBo Biotech Aktiengesellschaft (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008000252-A1 | NEW UREA DERIVATIVES AND THE APPLICATION THEREOF | SCHEBO BIOTECH AG (DE) | 2008-01-03 | — | — | WO | disclosed |
| WO-2008000252-A1 | NEW UREA DERIVATIVES AND THE APPLICATION THEREOF | SCHEBO BIOTECH AG (DE) | 2008-01-03 | — | — | WO | disclosed |