Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059366 | 1.00 | TP53 (0.42) | TP53GAAALOX15EHMT2MEN1 | |
| SCHEMBL4159132 | 1.00 | TP53 (0.42) | TP53GAAALOX15EHMT2MEN1 | |
| SCHEMBL4159129 | 1.00 | TP53 (0.42) | TP53GAAALOX15EHMT2MEN1 | |
| SCHEMBL4173458 | 1.00 | TP53 (0.42) | TP53GAAALOX15EHMT2MEN1 | |
| SCHEMBL4173459 | 1.00 | TP53 (0.42) | TP53GAAALOX15EHMT2MEN1 | |
| SCHEMBL4159136 | 1.00 | TP53 (0.42) | TP53GAAALOX15EHMT2MEN1 | |
| SCHEMBL4173465 | 1.00 | TP53 (0.42) | TP53GAAALOX15EHMT2MEN1 | |
| SCHEMBL4059372 | 1.00 | TP53 (0.42) | TP53GAAALOX15EHMT2MEN1 | |
| SCHEMBL4166683 | 0.88 | KLK7 (0.41) | TP53GAAALOX15MEN1KMT2A | |
| SCHEMBL4166677 | 0.88 | KLK7 (0.41) | TP53GAAALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009035553-A2 | ANALOGS OF TETRAMIC ACID | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2009-03-19 | — | — | WO | disclosed |