SCHEMBL4059526

SCHEMBL4059526

O=C(O)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(Cl)cc2)c1CN1CCCC1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.61
CNR2 P34972 16/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1039066 0.88 CNR1 (0.61) CNR1CNR2
SCHEMBL674863 0.86 CNR1 (0.82) CNR1CNR2
SCHEMBL6102985 0.84 CNR1 (0.67) CNR1CNR2
SCHEMBL1041298 0.84 CNR1 (0.72) CNR1CNR2
SCHEMBL6106568 0.83 CNR1 (0.68) CNR1CNR2
SCHEMBL10138883 0.81 CNR1 (0.74) CNR1CNR2
SCHEMBL4914879 0.79 CNR1 (0.61) CNR1CNR2
SCHEMBL661156 0.78 CNR1 (0.66) CNR1CNR2
SCHEMBL24238305 0.78 CNR1 (0.60) CNR1CNR2
SCHEMBL30961580 0.78 CNR1 (0.60) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2012775-A1 USE OF CBX CANNABINOID RECEPTOR MODULATORS AS POTASSIUM CHANNEL MODULATORS Solvay Pharmaceuticals GmbH (DE) 2009-01-14 EP claimed
WO-2007125049-A1 USE OF CBX CANNABINOID RECEPTOR MODULATORS AS POTASSIUM CHANNEL MODULATORS SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-08 WO claimed