SCHEMBL406091

SCHEMBL406091

O=[N+]([O-])/C=C/O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15930033 1.00
SCHEMBL27956 1.00
SCHEMBL2701677 0.76
SCHEMBL5957000 0.76
SCHEMBL2348400 0.72
SCHEMBL17574719 0.64
SCHEMBL2572328 0.64
SCHEMBL10348306 0.64
SCHEMBL10348305 0.64
SCHEMBL176 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10227286-B2 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones FMC CORPORATION (US) 2019-03-12 US disclosed
US-20180057442-A1 3-OXO-3-(ARYLAMINO)PROPANOATES, A PROCESS FOR THEIR PREPARATION, AND THEIR USE IN PREPARING PYRROLIDINONES FMC CORPORATION 2018-03-01 US disclosed
WO-2016182780-A1 ARYL SUBSTITUTED BICYCLIC COMPOUNDS AS HERBICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2016-11-17 WO disclosed
WO-2014047110-A2 SUBSTITUTED ALKYL DIARYL DERIVATIVES, METHODS OF PREPARATION AND USES TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2014-03-27 WO disclosed
US-20120065187-A1 HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE ALCON RESEARCH, LTD (US) 2012-03-15 US disclosed
US-20120065187-A1 HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE ALCON RESEARCH, LTD (US) 2012-03-15 US disclosed
US-20110257137-A1 HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE KALYPSYS, INC. (US) 2011-10-20 US disclosed
US-20110257137-A1 HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE KALYPSYS, INC. (US) 2011-10-20 US disclosed
US-20100120741-A1 HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-05-13 US disclosed
US-20100120741-A1 HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-05-13 US disclosed