SCHEMBL406111

SCHEMBL406111

Cc1ccc(C(=O)O)c([N+](=O)[O-])c1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.60
CYP3A4 P08684 2/20 0.60
ALDH1A1 P00352 4/20 0.50
GPR35 Q9HC97 1/20 0.50
DTYMK P23919 1/20 0.49
CSNK2A1 P68400 1/20 0.48
KCNMA1 Q12791 1/20 0.48
RXRA P19793 1/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
ALOX15 P16050 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CASP6 P55212 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6225779 0.86 MCL1 (0.54) TSHRCYP3A4ALDH1A1DTYMKKCNMA1
SCHEMBL29935450 0.85 DTYMK (0.62) TSHRCYP3A4ALDH1A1GPR35DTYMK
SCHEMBL149316 0.85 DTYMK (0.62) TSHRCYP3A4ALDH1A1GPR35DTYMK
SCHEMBL3112702 0.85 TSHR (0.60) TSHRCYP3A4ALDH1A1GPR35KCNMA1
SCHEMBL9542579 0.84 TSHR (0.58) TSHRCYP3A4ALDH1A1GPR35KCNMA1
SCHEMBL8494822 0.84 TSHR (0.58) TSHRCYP3A4ALDH1A1GPR35KCNMA1
Hydrochloric Acid SCHEMBL3730916 0.84 DTYMK (0.60) TSHRCYP3A4ALDH1A1DTYMKCSNK2A1
SCHEMBL8446509 0.84 DTYMK (0.60) TSHRCYP3A4ALDH1A1DTYMKCSNK2A1
SCHEMBL9542582 0.84 TSHR (0.58) TSHRCYP3A4ALDH1A1GPR35KCNMA1
Potassium Ion SCHEMBL11048083 0.84 DTYMK (0.60) TSHRCYP3A4ALDH1A1DTYMKCSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014111493-A1 SUBSTITUTED BENZIMIDAZOLYL PHOSPHINE COMPOUNDS AND A METHOD FOR DECARBOXYLATING CARBON-CARBON LINKING SALTIGO GMBH (DE) 2014-07-24 WO claimed
EP-2757106-A1 Substituted benzimidazole phosphine compounds and a method for decarboxylating carbon-carbon bond Saltigo GmbH (DE) 2014-07-23 EP claimed
US-RE34272-E Oxalic acid, a thiocyanate salt, and a nitrobenzenesulfonate salt REM CHEMICALS, INC. (US) 1993-06-08 US claimed
EP-0395815-B1 METHOD AND COMPOSITION FOR REFINEMENT OF METAL SURFACES REM CHEMICALS, INC. (US) 1993-06-02 EP claimed
EP-0395815-A1 Method and composition for refinement of metal surfaces REM CHEMICALS, INC. (US) 1990-11-07 EP claimed
US-4906327-A Method and composition for refinement of metal surfaces REM CHEMICALS, INC. (US) 1990-03-06 US claimed
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2025-07-24 US disclosed
CN-115066428-B Boric acid derivatives 首药控股(北京)股份有限公司 2025-06-13 CN disclosed
CN-116693416-B Aryloxy aminobenzoic acid derivative, and preparation method and application thereof 桂林医学院 2025-01-07 CN disclosed
WO-2024188246-A9 NITROGEN-CONTAINING MACROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海宇道生物技术有限公司 2024-12-05 WO disclosed
WO-2024188246-A1 NITROGEN-CONTAINING MACROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海宇道生物技术有限公司 2024-09-19 WO disclosed
CN-118451078-A Modified proteins and protein degrading agents 上海睿跃生物科技有限公司 2024-08-06 CN disclosed
CN-118307594-A Tricarbazole amine-based compound, self-assembled hole transport material containing compound and application of self-assembled hole transport material in perovskite solar cell 天合光能股份有限公司 2024-07-09 CN disclosed
EP-0213892-B1 HERBICIDALLY ACTIVE ENOLS ROHM AND HAAS COMPANY (US) 1992-03-25 EP disclosed
EP-0395815-A1 Method and composition for refinement of metal surfaces REM CHEMICALS, INC. (US) 1990-11-07 EP disclosed
EP-0371731-A2 Quinazolinone derivatives SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1990-06-06 EP disclosed
US-4906327-A Method and composition for refinement of metal surfaces REM CHEMICALS, INC. (US) 1990-03-06 US disclosed
US-4781750-A Herbicidally active enols ROHM AND HAAS COMPANY (US) 1988-11-01 US disclosed
EP-0213892-A2 Herbicidally active enols ROHM AND HAAS COMPANY (US) 1987-03-11 EP disclosed
US-3976639-A Intermediates for indoles HOFFMANN-LA ROCHE INC. (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, TP53BP1 TSHR 3311/4885CYP3A4 2487/4885ALDH1A1 2239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.