SCHEMBL4062285

SCHEMBL4062285

CCCCCCCCCCCCCCCCC(Br)CBr

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.46
PPARD Q03181 1/20 0.46
ZDHHC20 Q5W0Z9 1/20 0.46
ZDHHC2 Q9UIJ5 1/20 0.46
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
ZDHHC7 Q9NXF8 1/20 0.42
DNM1 Q05193 2/20 0.42
OPRM1 P35372 1/20 0.40
PLA2G1B P04054 1/20 0.40
PLA2G2A P14555 1/20 0.40
GPR84 Q9NQS5 3/20 0.38
FDPS P14324 3/20 0.38
SPHK1 Q9NYA1 1/20 0.38
FFAR1 O14842 1/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754267 1.00 LCK (0.46) LCKPPARDZDHHC20ZDHHC2LMNA
SCHEMBL1721008 1.00 LCK (0.46) LCKPPARDZDHHC20ZDHHC2LMNA
SCHEMBL874419 1.00 LCK (0.46) LCKPPARDZDHHC20ZDHHC2LMNA
SCHEMBL27892458 1.00 LCK (0.46) LCKPPARDZDHHC20ZDHHC2LMNA
SCHEMBL7875992 1.00 LCK (0.46) LCKPPARDZDHHC20ZDHHC2LMNA
SCHEMBL3493152 1.00 LCK (0.46) LCKPPARDZDHHC20ZDHHC2LMNA
SCHEMBL201351 0.97
SCHEMBL28999301 0.91 LCK (0.41) LCKPPARDZDHHC20ZDHHC2LMNA
SCHEMBL597769 0.89
SCHEMBL12214087 0.86 LCK (0.52) LCKPPARDZDHHC20ZDHHC2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2059496-A1 ACETYLENIC COMPOUNDS Commonwealth Scientific and Industrial Research Organisation (AU) 2009-05-20 EP claimed
WO-2008031157-A1 ACETYLENIC COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-03-20 WO claimed
EP-1540289-B1 METHOD AND DEVICE FOR THE CONTINUOUS DETERMINATION OF THE LUBRICATING OIL CONSUMPTION OF AN INTERNAL COMBUSTION ENGINE TOTAL MARKETING SERVICES (FR) 2016-07-20 EP disclosed
EP-2059496-A1 ACETYLENIC COMPOUNDS Commonwealth Scientific and Industrial Research Organisation (AU) 2009-05-20 EP disclosed
WO-2008031157-A1 ACETYLENIC COMPOUNDS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-03-20 WO disclosed
US-7291836-B2 Method and device for continuous determination of lubricating oil consumption of an internal combustion engine TOTALFINAELF FRANCE (FR) 2007-11-06 US disclosed
US-20050268692-A1 Method and device for continuous determination of lubricating oil consumption of an internal combustion engine TOTALFINAELF FRANCE (FR) 2005-12-08 US disclosed
US-6294389-B1 Furnace for an engine exhaust measurement system GENERAL MOTORS CORPORATION 2001-09-25 US disclosed
US-5445964-A Dynamic engine oil and fuel consumption measurements using tunable diode laser spectroscopy GENERAL MOTORS CORPORATION 1995-08-29 US disclosed
US-4990780-A Method for determining fuel and engine oil comsumption using tunable diode laser spectroscopy GENERAL MOTORS CORPORATION (US) 1991-02-05 US disclosed
US-4784797-A ALDEHYDE REACTED WITH DIAMINE FOLLOWED BY SALT FORMATION OR QUATERNIZATION THE DOW CHEMICAL COMPANY (US) 1988-11-15 US disclosed
US-4784796-A REACTION OF UNSATURATED ALDEHYDE WITH DIAMINE, FURTHER REACTED WITH CARBOXYLIC ACID OR QUATERNIZATION THE DOW CHEMICAL COMPANY (US) 1988-11-15 US disclosed
US-4460682-A NONDIFFUSING COBALT(III) COMPLEX KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-07-17 US disclosed