Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717648 | 0.89 | HTT (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4062444 | 0.87 | KDM4E (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28188288 | 0.87 | CA1 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6740070 | 0.87 | KMT2A (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8381595 | 0.87 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28180336 | 0.85 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28667937 | 0.83 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6535999 | 0.83 | HK2 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29034612 | 0.82 | MEN1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28788991 | 0.82 | MEN1 (0.50) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101267811-B | Novel multi-cyclic compounds and their use | REVOTAR BIOPHARMACEUTICALS AG | 2012-07-25 | — | — | CN | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| CN-101267811-A | Novel multi-cyclic compounds and their use | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2008-09-17 | — | — | CN | disclosed |