Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 17/20 | 0.64 |
| ▸ | CX3CR1 | P49238 | 14/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063457 | 0.83 | CXCR2 (0.53) | CXCR2CX3CR1 | |
| SCHEMBL9902065 | 0.83 | CXCR2 (0.45) | CXCR2CX3CR1 | |
| SCHEMBL213766 | 0.78 | CXCR2 (1.00) | CXCR2CX3CR1ADORA1 | |
| SCHEMBL4129653 | 0.78 | CXCR2 (1.00) | CXCR2CX3CR1ADORA1 | |
| SCHEMBL213886 | 0.78 | CXCR2 (1.00) | CXCR2CX3CR1ADORA1 | |
| SCHEMBL212748 | 0.78 | CXCR2 (1.00) | CXCR2CX3CR1ADORA1 | |
| SCHEMBL4056044 | 0.75 | CXCR2 (0.35) | CXCR2CX3CR1 | |
| SCHEMBL9905776 | 0.75 | CXCR2 (0.37) | CXCR2CX3CR1 | |
| SCHEMBL9902066 | 0.75 | CXCR2 (0.41) | CXCR2CX3CR1DAO | |
| SCHEMBL9905763 | 0.74 | CXCR2 (0.37) | CXCR2CX3CR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120140-A1 | NOVEL 5,7-DISUBSTITUTED [1,3]THIAZOLO[4,5-D]PYRIMIDIN-2(3H)-ONE DERIVATIVES 258 | ASTRAZENECA AB (SE) | 2009-10-01 | — | — | WO | disclosed |