Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 18/20 | 0.62 |
| ▸ | IGF1R | P08069 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400791 | 0.94 | TNK2 (0.69) | TNK2IGF1RCYP3A4 | |
| SCHEMBL400115 | 0.92 | IGF1R (0.65) | TNK2IGF1RCYP3A4 | |
| SCHEMBL27961665 | 0.92 | TNK2 (0.59) | TNK2IGF1RCYP3A4 | |
| Carbamic Acid SCHEMBL4073401 | 0.88 | IGF1R (0.65) | TNK2IGF1RCYP3A4 | |
| Carbamic Acid SCHEMBL4063099 | 0.88 | IGF1R (0.69) | TNK2IGF1RCYP3A4 | |
| SCHEMBL4069402 | 0.86 | IGF1R (0.62) | TNK2IGF1RCYP3A4 | |
| SCHEMBL400025 | 0.86 | TNK2 (0.66) | TNK2IGF1RCYP3A4 | |
| Carbamic Acid SCHEMBL4060715 | 0.85 | IGF1R (0.61) | TNK2IGF1RCYP3A4 | |
| Carbamic Acid SCHEMBL4069846 | 0.85 | TNK2 (0.67) | TNK2 | |
| SCHEMBL399524 | 0.84 | IGF1R (0.66) | TNK2IGF1RCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740591-B1 | 6,6-BICYCLIC RING SUBSTITUTED HETEROBICYCLIC PROTEIN KINASE INHIBITORS | OSI PHARM INC (US) | 2009-06-17 | — | — | EP | claimed |